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Activitate didactica
Facultatea de Biologie, Universitatea din Bucuresti
Biofizica - curs Licență in Biologie/Ecologie, anul II
Microscopie biomedicala - curs Master de Neurobiologie (master de cercetare), anul I
Neurobiologie medicala - curs Master de Neurobiologie (master de cercetare), anul II
Principii si tehnici analitice in biochimia clinica - curs Master Biochimie Clinica Aplicata (master profesional), anul I
Activitate stiintifica
Scopus ID : 8379627700; Indice Hirsch (Scopus): 16
Proiecte in derulare (Director proiect):
PCE 39/2022, Profilul de siguranta pentru doua antiepileptice nou-aprobate prin analiza in vitro a riscului proaritmogen
si a transportului prin BBB, http://episafe.unibuc.ro/
POIM 146/2022, SMIS 147035, Cresterea capacitatii Universitatii din Bucuresti in vederea gestionarii pandemiei generate
de virusul SARS-COV-2, https://protectie-covid.unibuc.ro/
Lista de lucrări ştiinţifice publicate
Articole ISI, ca autor principal (prim autor, autor corespondent, ultim autor)
1. Radu BM, Bacalum M, Marin A, Chifiriuc CM, Lazar V, Radu M. (2011) Mechanisms of ceftazidime and ciprofloxacin transport through porins in multidrug-resistance developed by extended-spectrum beta-lactamase E.coli strains, J Fluoresc. 21(4):1421-9.
2. Radu BM, Dumitrescu DI, Mustaciosu CC, Radu M (2012) Dual effect of methylglyoxal on the intracellular Ca(2+) signaling and neurite outgrowth in mouse sensory neurons. Cell Mol Neurobiol32(6):1047-57
3. Radu BM, Bramanti P, Osculati F, Flonta ML, Radu M, Bertini G, Fabene PF. (2013) Neurovascular unit in chronic pain. Mediators Inflamm. 2013:64826
4. Radu BM, Iancu AD, Dumitrescu DI, Flonta ML, Radu M. (2013) TRPV1 properties in thoracic dorsal root ganglia neurons are modulated by intraperitoneal capsaicin administration in the late phase of type-1 autoimmune diabetes. Cell Mol Neurobiol 33(2):187-196.
5. Radu BM, Dumitrescu DI, Marin A, Banciu DD, Iancu AD, Selescu T, Radu M. (2014) Advanced type 1 diabetes is associated with ASIC alterations in mouse lower thoracic dorsal root ganglia neurons. Cell Biochem Biophys. 68(1):9-23.
6. Campeanu RA#, Radu BM#, Cretoiu SM, Banciu DD, Banciu A, Cretoiu D, Popescu LM. (2014) Near-infrared low level laser stimulation of telocytes from human myometrium. Lasers Med Sci. 29(6):1867-74. contributii egale cu primul autor
7. Cretoiu SM#, Radu BM#, Banciu A, Banciu DD, Cretoiu D, Ceafalan LC, Popescu LM. (2015) Isolated human uterine telocytes: immunocytochemistry and electrophysiology of T-type calcium channels. Histochem Cel Biol 143(1):83-94. contributii egale cu primul autor
8. Radu BM, Radu M, Tognoli C, Benati D, Merigo F, Assfalg M, Solani E, Stranieri C, Ceccon A, Fratta Pasini AM, Cominacini L, Bramanti P, Osculati F, Bertini G, Fabene PF. (2015) Are they in or out? The elusive interaction between Qtracker ® 800 vascular labels and brain endothelial cells. Nanomedicine (Lond). 10(22):3329-42.
9. Cretoiu D#, Radu BM#, Banciu A, Banciu D, Cretoiu SM. (2017) Telocytes heterogeneity: From cellular morphology to functional evidence. Semin Cell Dev Biol. 64:26-39. contributii egale cu primul autor
10. Radu BM, Banciu A, Banciu DD, Radu M, Cretoiu D, Cretoiu SM. (2017) Calcium Signaling in Interstitial Cells: Focus on Telocytes. Int J Mol Sci. 18(2).
11. Radu BM, Epureanu FB, Radu M, Fabene PF, Bertini G. (2017) Nonsteroidal anti-inflammatory drugs in clinical and experimental epilepsy. Epilepsy Res. 131:15-27.
12. Radu BM, Osculati AMM, Suku E, Banciu A, Tsenov G, Merigo F, Di Chio M, Banciu DD, Tognoli C, Kacer P, Giorgetti A, Radu M, Bertini G, Fabene PF. (2017) All muscarinic acetylcholine receptors (M1-M5) are expressed in murine brain microvascular endothelium. Sci Rep. 7(1):5083.
13. Banciu A, Banciu DD, Mustaciosu CC, Radu M, Cretoiu D, Xiao J, Cretoiu SM, Suciu N, Radu BM. (2018) Beta-Estradiol Regulates Voltage-Gated Calcium Channels and Estrogen Receptors in Telocytes from Human Myometrium. Int J Mol Sci. 19(5) :1413
14. Mustăciosu CC, Banciu A, Rusu CM, Banciu DD, Savu D, Radu M, Radu BM. (2019) RNA-Binding Proteins HuB, HuC, and HuD are Distinctly Regulated in Dorsal Root Ganglia Neurons from STZ-Sensitive Compared to STZ-Resistant Diabetic Mice. Int J Mol Sci. 20(8) :1965.
15. Predescu DV, Crețoiu SM, Crețoiu D, Pavelescu LA, Suciu N, Radu BM@, Voinea SC. (2019) G Protein-Coupled Receptors (GPCRs)-Mediated Calcium Signaling in Ovarian Cancer: Focus on GPCRs activated by Neurotransmitters and Inflammation-Associated Molecules. Int J Mol Sci. 20(22): 5568, @autor corespondent.
16. Caravia L#, Staicu CE#, Radu BM#, Condrat CE, Crețoiu D, Bacalbașa N, Suciu N, Crețoiu SM, Voinea SC. (2020) Altered Organelle Calcium Transport in Ovarian Physiology and Cancer. Cancers (Basel). 12(8):2232. #contributii egale
17. Amuzescu B, Airini R, Epureanu FB, Mann SA, Knott T, Radu BM. (2021) Evolution of mathematical models of cardiomyocyte electrophysiology. Math Biosci. 334:108567.
18. Staicu CE, Jipa F, Axente E, Radu M, Radu BM@, Sima F. (2021) Lab-on-a-Chip Platforms as Tools for Drug Screening in Neuropathologies Associated with Blood-Brain Barrier Alterations. Biomolecules. 11(6):916. @autor corespondent.
19. Thomet U, Amuzescu B, Knott T, Mann SA, Mubagwa K, Radu BM. (2021) Assessment of proarrhythmogenic risk for chloroquine and hydroxychloroquine using the CiPA concept. Eur J Pharmacol. 913:174632.
Articole în reviste cotate ISI, ca și contributor
1. Neagoe I, Macri B, Flonta ML (2004) Hyperici herba extract interaction with artificial lipid bilayers, J Pharmac Pharmacol, 56(10):1283-9.
2. Neaga E, Amuzescu B, Dinu C, Macri B, Pena F, Flonta ML. (2005) Extracellular trypsin increases ASIC1a selectivity for monovalent versus divalent cations, J Neurosci Meth, 144:241-248.
3. Loucif AJ, Bonnavion P, Macri B, Golmard JL, Boni C, Melfort M, Leonard G, Lesch KP, Adrien J, Jacquin TD. (2006) Gender-dependent regulation of G-proteingated inwardly rectifying potassium current in dorsal raphe neurons in knock-out mice devoid of the 5-hydroxytryptamine transporter. J Neurobiol. 66(13):1475-88.
4. Nae M, Gazdaru D, Acasandrei A, Georgescu R, Macri B, Radu M. (2008) A fluorescence approach of the gamma radiations effects on gramicidin A channels inserted in liposomes. J Pept Sci14(9):1003-1009.
5. Avram S, Duda-Seiman D, Borcan F, Radu B, Duda-Seiman C, Mihailescu D. (2011) Evaluation of antimicrobial activity of the new mastoparan derivatives by using QSAR and computational mutagenesis, Int J Pept Res Ther. 17:7-17
6. Cretoiu SM, Cretoiu D, Marin A, Radu BM, Popescu LM (2013) Telocytes: ultrastructural, immunohistochemical and electrophysiological characteristics in human myometrium, Reproduction, 145(4):357-370.
7. Bertini G, Bramanti P, Constantin G, Pellitteri M, Radu BM, Radu M, Fabene PF. (2013) New players in the neurovascular unit: Insights from experimental and clinical epilepsy. Neurochem Int. 63(7):652-659.
8. Roatesi I, Radu BM, Cretoiu D, Cretoiu SM. (2015) Uterine Telocytes: A Review of Current Knowledge. Biol Reprod. 93(1):10.
9. Mann SA, Heide J, Knott T, Airini R, Epureanu FB, Deftu AF, Deftu AT, Radu BM, Amuzescu B. (2019) Recording of multiple ion current components and action potentials in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp. Journal of Pharmacology and Toxicology. 100:106599.
10. Staicu CE, Predescu DV, Rusu CM, Radu BM, Cretoiu D, Suciu N, Cretoiu SM, Voinea SC (2020) Role of microRNAs as clinical cancer biomarkers for ovarian cancer: a short overview. Cells, 9(1):169.
11. Staicu CE, Jipa F, Porosnicu I, Bran A, Stancu E, Dobrea C, Radu BM, Axente E, Tiseanu I, Sima F, Sugioka K (2022) Glass lab-on-a-chip platform fabricated by picosecond laser for testing tumor cells exposed to X-ray radiation, Applied Physics A, 128: 770
Capitole în cărți/volume, în edituri internaționale
1. Macri BM, Stoian G, Flonta ML. (2006) Active compounds from Hyperici herba: traditional versus modern knowledge. In Recent progress in medicinal plants, volume 13 (Search for Natural Products), editors Govil JN, Singh VK, Arunachalam C, pp. 339-355. Studium Press, Houston, ISBN 0-9761849-5-8
2. Radu BM, Banciu A, Banciu DD, Radu M. (2016) Chapter 4. Acid Sensing Ion Channels as Potential Pharmacological Targets in Peripheral and Central Nervous System Diseases. Adv Protein Chem Struct Biol. 103:137-67. in Ion Channels as Therapeutic Targets, Part A, editor Rossen Donev, Academic Press, ISBN: 978-0-12-804794-1.
3. Banciu DD, Banciu A, Radu BM. (2016) Chapter 19. Electrophysiological Features of Telocytes. Adv Exp Med Biol. 913:287-302. in Telocytes Connecting cells, editors Xiangdong Wang, Dragos Cretoiu. Springer ISSN 0065-2598, ISBN 978-981-10-1060-6
4. Dumitru A, Radu BM, Radu M, Cretoiu SM (2018) Section II, Basic aspects of muscle atrophy, 4. Muscle changes during atrophy, Adv Exp Med Biol. 1088, in Muscle atrophy, editor Junjie Xiao, Springer Nature ISSN 0065-2598, ISBN 978-981-13-1434-6
5. Dumitru A, Toader DO, Cretoiu SM, Cretoiu D, Suciu N, Radu BM (2018) Chapter 8. Alterations in Calcium Signaling Pathways in Breast Cancer, in Calcium and Signal Transduction, Editors John N. Buchholz and Erik J. Behringer, InTech, doi:10.5772/intechopen.80811, ISBN: 978-1-78984-250-0, Print ISBN: 978-1-78984-249-4
6. Voichitoiu AD#, Radu BM#, Pavelescu L, Cretoiu D, Deftu AT, Suciu N, Cretoiu SM. (2019) Extracellular Vesicles in Cancer, in Extracellular Vesicles and their importance in human health, InTechOpen, DOI: 10.5772/intechopen.85117, #contribuţii egale cu primul autor
7. Deftu AT#, Radu BM#, Cretoiu D, Deftu AF, Cretoiu SM, Xiao J. (2020) Exosomes as intercellular communication messengers for cardiovascular and cerebrovascular diseases, in Exosomes. A Clinical Compendium. editors Larry Edelstein and Denis Noble, Elsevier, ISBN: 978-0-12-816053-4, #contribuţii egale cu primul autor
8. Stoica R, Rusu CM, Staicu CE, Burlacu AE, Radu M, Radu BM. (2021) Ca2+ homeostasis in brain microvascular endothelial cells. Int Rev Cell Mol Biol. 2021;362:55-110, in Inter-Organellar Ca2+ Signaling in Health and Disease - Part A, editors Saverio Marchi and Lorenzo Galluzzi, Elsevier, ISBN: 978-0-12-824034-2
Brevete
1. Bogdan Amuzescu, Beatrice Mihaela Radu, Dan Florin Mihăilescu, Stefan Mann (2020), ”Method for in vitro detection of the proarrhythmogenic risk of a drug candidate on human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM)”, Brevet EP3546935B1/23.12.2020, acordat de European Patenting Office (EPO), https://patents.google.com/patent/EP3546935B1/en
