Bogdan P. Amuzescu, MD (1991), PhD (2003) researcher of ion channel biophysical properties, mathematical modeling of complex biological systems. Fellowships at Katholieke Universiteit Leuven (2000-2003). Currently associate professor at Dept. Biophysics & Physiology, Faculty of Biology, University of Bucharest. Managerial experience: advisory board member of the Romanian Society of Neuroscience (2004-2012), Romanian Society against Epilepsy (since 2015). Research of biophysical and pharmacological properties of ENaC/Deg and TRP channels, applied research in cardiac electrophysiology and cardiac safety drug testing.  Several awards and honors, such as the First prize of Romanian Neuroscience Society, co-chair of a platform session on cardiac electrophysiology at the 53rd BPS meeting. Editorial member of several reputed journals like European Journal of Biophysics & expert reviewer for journals like European Journal of Pharmacology. Author of over 40 research articles, 6 books or book chapters. Member of Biophysical Society, AAAS, FENS, and other scientific societies.

Selected publications:

Amuzescu B., Segal A., Flonta M-L., Simaels J., Van Driessche, W. (2003): Zinc is a voltage-dependent blocker of native and heterologously expressed epithelial Na+ channels. Pflügers Arch. 446: 69-77

Gwanyanya A., Amuzescu B., Zakharov S., Macianskiene R., Sipido K., Bolotina V., Vereecke J., Mubagwa K. (2004): Magnesium-inhibited, TRPM6/7-like channels in cardiac myocytes: permeation of divalent cations and pH-mediated regulation. J Physiol. 559(3): 761-776

Marin A., Prica C., Amuzescu B., Neaga E., Flonta M.-L. (2008): ASIC1a activation by amitriptyline and FMRF-amide is removed by serine proteases, Channels (6):419-428.

Scheel O., Frech S., Amuzescu B., Eisfeld J., Lin K.-H., Knott T. (2014): Action potential characterization of human induced pluripotent stem cell-derived cardiomyocytes using automated patch-clamp technology, Assay Drug Dev Technol. 12(8):457-69

Iordache F., Constantinescu A., Andrei E., Amuzescu B., Halitzchi F., Savu L., Maniu H. (2016): Electrophysiology, immunophenotype, and gene expression characterization of senescent and cryopreserved human amniotic fluid stem cells, J. Physiol. Sci. 66:463-476

Mann S.A., Heide J., Knott T., Airini R., Epureanu F.B., Deftu A.-F., Deftu A.-T., Radu B.M., Amuzescu B. (2019): Recording of multiple ion current components and action potentials in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp, J. Pharmacol. Toxicol. Meth. 100:106599

Airini R., Iordache F., Alexandru D., Savu L., Epureanu F.B., Mihailescu D., Amuzescu B., Maniu, H.: Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes, J. Cell. Mol. Med. 23(11):7233-7245

Iacobas S., Amuzescu B., Iacobas D.A. (2021): Transcriptomic uniqueness and commonality of the ion channels and transporters in the four heart chambers, Sci. Rep. 11(1):2743

Amuzescu B., Airini R., Epureanu F.B., Mann S.A., Knott T., Radu B.M. (2021): Evolution of mathematical models of cardiomyocyte electrophysiology, Math. Biosci. 334:108567

Thomet U., Amuzescu B., Knott T., Mann S.A., Mubagwa K., Radu B.M. (2021):  Assessment of proarrhythmogenic risk for chloroquine and hydroxychloroquine using the CiPA concept, Eur. J. Pharmacol. 913:174632

Mateias A.L., Armasescu F., Amuzescu B., Corlan A.D., Radu B.M. (2024): Inhibitory effects of cenobamate on multiple human cardiac ion channels and possible arrhythmogenic consequences, Biomolecules 14:1582 (19 p.) https://doi.org/10.3390/biom14121582

Armasescu F., Amuzescu B., Gheorghe R.-O., Ghenghea M., Ristoiu V., Ciurea J., Gruia I. (2025): Fiber-optic-guided near-infrared laser exposure induces depolarization of cultured primary sensory neurons and modifies biophysical properties of human Nav1.5 channels, J Photochem Photobiol B 269:113191 (12 p.) https://doi.org/10.1016/j.jphotobiol.2025.113191